Af­ter get­ting crushed by bad da­ta, Zyner­ba says its cannabis-based drug worked on Frag­ile X symp­toms

Less than two months since a pair of mid-stage set­backs crushed its stock price, re­searchers at Zyner­ba $ZYNE say they had bet­ter re­sults from a small Phase II study that test­ed their cannabis-based ther­a­py on symp­toms of Frag­ile X syn­drome. And the news quick­ly sparked a big ral­ly for its bat­tered stock.

Of­ten com­pared to GW Phar­ma­ceu­ti­cals, which has had some strik­ing suc­cess­es in the field, Zyner­ba set out to see what im­pact their cannabid­i­ol ther­a­py would have tamp­ing down on a range of com­mon symp­toms for Frag­ile X, in­clud­ing anx­i­ety and de­pres­sion. And with 20 pa­tients in the sin­gle-arm study, the in­ves­ti­ga­tors say they hit their pri­ma­ry with a 46% drop in their ADAMS score, track­ing Anx­i­ety, De­pres­sion, and Mood Scale.

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