An Ox­ford spin­out rais­es $44M as it looks to res­ur­rect an old Roche an­ti­body in pur­suit of a rare dis­ease

Three months ago, a small and lit­tle-known Ox­ford Uni­ver­si­ty spin­out called Celleron an­nounced they would try to res­ur­rect an an­ti­body Roche re­tired back in 2018. Now that spin­out is spin­ning out its own new com­pa­ny and rais­ing cash from a high-pro­file in­vestor to push that an­ti­body through the clin­ic.

Backed with €37 mil­lion in Se­ries A cash, Syn­Ox Ther­a­peu­tics will look to de­vel­op the an­ti­body, known as emac­tuzum­ab, for tenosyn­ovial gi­ant cell tu­mours (TGCT), a rare dis­ease where se­ries of be­nign tu­mors be­gin to grow around the joints and ten­dons. Health­Cap and Medicxi led the round and were joined by For­bion and Gimv.

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