AACR21: Eli Lil­ly blazes new trail for RET in­hibitor, gin­ning up a re­sponse in 9 sol­id tu­mor types in ear­ly da­ta

Eli Lil­ly was first to mar­ket with its RET fu­sion-in­hibitor Retev­mo in May, stak­ing its claim in the rare tu­mor in­di­ca­tion. But Roche wasn’t far on its heels with an ap­proval of its own for RET in­hibitor Gavre­to, and now Lil­ly is look­ing to get the leg up on its clos­est com­peti­tor.

Lil­ly’s Retev­mo post­ed a 47% ob­jec­tive re­sponse rate with re­spons­es in nine unique RET fu­sion-pos­i­tive tu­mor types, ac­cord­ing to ear­ly da­ta from the Phase I/II LI­BRET­TO-001 un­veiled Sun­day at the vir­tu­al AACR meet­ing.

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