Fol­low­ing Ver­tex pact, Par­i­on strikes an­oth­er rich col­lab­o­ra­tion — this time with Shire

Two years af­ter Durham, NC-based Par­i­on Sci­ences forged a ma­jor tie-up with Ver­tex on cys­tic fi­bro­sis, the lit­tle biotech has done it again — this time with Shire.

Lex­ing­ton, MA-based Shire has agreed to pay $40 mil­lion in an up­front and near-term cash to get its hands on world­wide rights to a Phase II dry eye dis­ease drug. Hun­dreds of mil­lions more is on the ta­ble in promised mile­stones, bring­ing the po­ten­tial deal val­ue up to $535 mil­lion.

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