GSK must pay As­traZeneca roy­al­ties on Ze­ju­la, UK court rules

GSK must pay roy­al­ties to As­traZeneca on to­tal sales of its ovar­i­an can­cer drug Ze­ju­la, a UK court ruled on Wednes­day.

The case traces back to a li­cens­ing deal Tesaro struck with As­traZeneca back in 2012 — years be­fore it was snapped up by GSK for $5.1 bil­lion — which led to the ap­proval of Ze­ju­la in 2017 for re­cur­rent ep­ithe­lial ovar­i­an, fal­lop­i­an tube or pri­ma­ry peri­toneal can­cer. The PARP in­hibitor has picked up a hand­ful of la­bel ex­pan­sions, in­clud­ing as a first-line main­te­nance ther­a­py for ad­vanced ovar­i­an can­cer and as a fourth-line treat­ment, though that in­di­ca­tion has since been pulled.

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