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Little Dermira’s shares zoom up on promising PhIIb atopic dermatitis data — but the road ahead is ultra risky and flanked by heavily armed giants

Just over 18 months since Dermira agreed to pay Roche some $135 million in near-term cash for its disappointing IL-13 anti-inflammatory drug lebrikizumab, hustling it straight into a $200 million mid-stage study for atopic dermatitis, the biotech claims to have the efficacy data to back up its claims that they have a blockbuster on their hands.

Now they’re running it into a pivotal program, long after the drug floundered in asthma under the pharma giant.

Little Dermira is taking on the 600-pound gorilla in atopic dermatitis: the IL-13/IL-4 drug Dupixent, from Regeneron and Sanofi. And it won’t be easy.


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Research Scientist - Immunology
Recursion Pharmaceuticals Salt Lake City, UT
Director of Operations
Atlas Venture Cambridge, MA

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