Mer­ck walks away from KalVista, who turns their sights on HAE

Two months af­ter KalVista an­nounced its di­a­bet­ic mac­u­lar ede­ma drug failed a Phase II tri­al, its big-name part­ner, Mer­ck, has end­ed their up-to-$760 mil­lion deal.

Signed in 2017, that deal didn’t make KalVista – they had al­ready land­ed $33 mil­lion from mar­quee ven­ture firms, in­clud­ing No­vo A/S and SV Life Sci­ences – but it turned the biotech from a mi­cro­cap that had re­verse-merged its way on­to pub­lic mar­kets in­to a name in­vestors knew. Lead drug KVD001 was about to go in­to Phase II. Mer­ck paid $37 mil­lion up­front, more than KalVista’s val­u­a­tion at the time, to back the drug’s de­vel­op­ment and for the op­tion to pick up or walk away from it once Phase II da­ta was in.

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