Less than four months af­ter a $55 mil­lion raise, Seer is ready to go pub­lic.

The com­pa­ny, run by Omid Farokhzad, filed for a $150 mil­lion IPO on Thurs­day as it pre­pares to jump on­to the Nas­daq. Seer’s stock tick­er will be fair­ly sim­ple to re­mem­ber — $SEER — and the move comes af­ter the com­pa­ny has raised more than $150 mil­lion since be­ing found­ed in 2017.

Thurs­day’s news al­so comes less than a month af­ter Seer’s main prod­uct, the Pro­teo­graph Prod­uct Suite, was de­liv­ered to one of its first col­lab­o­ra­tors, per the com­pa­ny’s S-1. Funds from the IPO will go to­ward fur­ther com­mer­cial­iz­ing the prod­uct and oth­er R&D-re­lat­ed projects for Pro­teo­graph.

The prod­uct’s main func­tion is to uti­lize nanopar­ti­cles to an­a­lyze the pro­tein com­po­si­tions in a blood sam­ple. Seer de­scribed the tech­nol­o­gy to End­points News in Ju­ly as a se­quenc­ing ma­chine read­ing out the base pairs on a par­tic­u­lar strand of DNA.

Last month, Nas­daq head of health­care list­ings Jor­dan Saxe pinned the to­tal num­ber of biotech IPOs through mid-Oc­to­ber at 72, with a to­tal com­bined raise high­er than $13.2 bil­lion. — Max Gel­man

IN8bio post­pones IPO amid record year for pub­lic de­buts

Af­ter more than 72 biotechs hopped on­to the Nas­daq this year, bring­ing in a record raise of more than $13 bil­lion, IN8bio de­cid­ed not to make the jump, af­ter all.

The New York-based biotech said on Fri­day that it’s post­pon­ing its IPO plans. It ini­tial­ly filed in Oc­to­ber for an $86 mil­lion raise, then set terms last week that would al­low it to bring in $75 mil­lion from 4.7 mil­lion shares at a price range of $15 to $17.

IN8bio didn’t of­fer an ex­pla­na­tion for the hold-up. It’s fo­cused on ge­net­i­cal­ly mod­i­fied gam­ma delta T cell ther­a­pies, and has two can­di­dates in the clin­ic for glioblas­toma and leukemia, re­spec­tive­ly.

INB-200, for new­ly di­ag­nosed glioblas­toma, was ad­min­is­tered to the first pa­tient in a Phase I tri­al in June. Last month, IN8bio said it ex­pect­ed to read out the first da­ta from that pro­gram in 2021. It planned on tag­ging $22 to $28 mil­lion in IPO pro­ceeds to see the can­di­date to Phase II, ac­cord­ing to an S-1/A fil­ing. 

The com­pa­ny had des­ig­nat­ed $10 to $17 mil­lion for INB-100, its leukemia can­di­date. That pro­gram be­gan dos­ing pa­tients in May, and IN8bio ex­pect­ed it to pro­duce ear­ly da­ta to­ward the end of 2022.

Nas­daq head of health­care list­ings Jor­dan Saxe told End­points News at the end of last month that fin­ish­ing the year with 75 biotech IPOs and just un­der $14 bil­lion in pro­ceeds would be a “fair es­ti­mate.” — Nicole De­Feud­is 

New York City is investing $20 million in biotech this year in the form of a 50,000-square-foot “innovation space” at the Brooklyn Navy Yard, complete with offices, research laboratories and events and programming space to grow biotech startups and companies.

Mayor Eric Adams said during his State of The City Address last Thursday that there will be an “emphasis” on making more opportunities for women and people of color to further diversify the industry. The City first reported the news.

Boehringer Ingelheim uncorked some positive results suggesting that Spevigo can help prevent flare-ups in patients with a severe form of psoriasis, months after the drug was approved to treat existing flares.

Spevigo, an IL-36R antibody also known as spesolimab, met its primary and a key secondary endpoint in the Phase IIb EFFISAYIL 2 trial in patients with generalized pustular psoriasis (GPP), Boehringer announced on Monday. While the company is keeping the hard numbers under wraps until later this year, it said in a news release that it anticipates sharing the results with regulators.

AstraZeneca, Novo Nordisk, and Sanofi won an appeals court win on Monday, as the US Court of Appeals for the Third Circuit found that the companies cannot be forced to provide 340B-discounted drugs purchased by hospitals from an unlimited number of community and specialty pharmacies.

“Legal duties do not spring from silence,” the decision says as the court makes clear that the federal government’s interpretation of the “supposed requirement” that the 340B program compels drugmakers to supply their discounted drugs to an unlimited number of contract pharmacies is not correct, noting:

A US appeals court has ruled against Johnson & Johnson’s use of bankruptcy to deal with mounting talc lawsuits, deciding that doing so would “create a legal blind spot.”

The Third Circuit Court of Appeals reversed a previous bankruptcy court decision on Monday, calling for the dismissal of a Chapter 11 filing by J&J’s subsidiary LTL Management.

Faced with more than 38,000 lawsuits alleging its talc-based products caused cancer, J&J spun its talc liabilities into a separate company called LTL Management back in October 2021 and filed for bankruptcy, a controversial move colloquially referred to as a “Texas two-step” bankruptcy. Claimants argued that the strategy is a misuse of the US bankruptcy code — and on Monday, a panel of judges agreed.