Laura Shawver, Silverback CEO

Or­biMed-backed Sil­ver­back, three months af­ter hack­ing the pipeline, re­verse-merges with small al­ler­gy biotech

Six years af­ter be­ing found­ed, a Seat­tle biotech backed by Or­biMed is say­ing good­bye in a clas­sic re­verse merg­er — while an­oth­er jumps to Nas­daq.

Sil­ver­back Ther­a­peu­tics put out word Thurs­day af­ter­noon that the Seat­tle biotech is re­verse-merg­ing with ARS Phar­ma­ceu­ti­cals, with the new com­pa­ny keep­ing the ARS name and trad­ing un­der the tick­er $SPRY.

Sil­ver­back had fall­en on hard times ear­li­er this year, ax­ing its two lead I/O can­di­dates to send it back to the pre­clin­i­cal draw­ing board and lay­ing off 27% of its staff back in April. At the time, Sil­ver­back re­port­ed that it was drop­ping the can­di­dates af­ter a Phase I/Ib study showed that one of them, go­ing af­ter HER2, had a re­duced abil­i­ty to kill tu­mors and al­so showed too many cy­tokine-re­lat­ed side ef­fects. The oth­er can­di­date was us­ing the same tech­nol­o­gy for a dif­fer­ent tar­get.

Endpoints News

Unlock this article instantly by becoming a free subscriber.

You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.