Porges sees the pros — and cons — for Bio­gen in Lil­ly’s Alzheimer’s sna­fu; Idera forges de­vel­op­ment pact; UK gov­ern­ment adds more cash for R&D pro­grams

 

Leerink’s Ge­of­frey Porges had some good news and some bad news to re­late to Bio­gen $BI­IB on Fri­day. The good news is that Eli Lil­ly’s flop heard round the world on Alzheimer’s with their lat­est Phase III for solanezum­ab means that a suc­cess for ad­u­canum­ab would be worth much, much more now in terms of po­ten­tial rev­enue, now that the phar­ma gi­ant is out of the game. The bad news: Now that Lil­ly $LLY has thrown even more cold wa­ter on the amy­loid be­ta the­o­ry be­hind the mem­o­ry-wast­ing dis­ease, ad­u­canum­ab is far less like­ly to suc­ceed — even though it’s a dis­tinct­ly dif­fer­ent pro­gram. Porges cut his prob­a­bil­i­ty of suc­cess from a quite high 65% to a quite low 35%.

Endpoints News

Unlock this article instantly by becoming a free subscriber.

You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.