A rad­i­cal­ly in­ex­pen­sive, non-prof­it ap­proach can trans­form drug R&D? Now, wait a minute…

The Drugs for Ne­glect­ed Dis­eases ini­tia­tive (DN­Di) isn’t just out to de­vel­op new ther­a­pies to help the world’s poor. It be­lieves it is on track to, in the words of ex­ec­u­tive di­rec­tor Bernard Pé­coul, “demon­strate that a dif­fer­ent mod­el is pos­si­ble for R&D.”

Work­ing with a col­lab­o­ra­tive mod­el, the non-prof­it has cre­at­ed a net­work of aca­d­e­mics, gov­ern­ment agen­cies and phar­ma com­pa­nies which to­geth­er have gained ap­proval for 6 ther­a­pies and put an­oth­er 26 in the clin­ic, ac­cord­ing to a fea­ture on the DN­Di in Na­ture which bull­ish­ly en­dors­es the alt-R&D ini­tia­tive. The group did that with a bud­get of $290 mil­lion, which Na­ture pegs as one quar­ter the cost of a sin­gle de­vel­op­ment ef­fort in phar­ma land.  Suerie Moon, a glob­al-health re­searcher at the Har­vard T.H. Chan School of Pub­lic Health and DN­Di board mem­ber told Na­ture:

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