Trendy Mod­er­na's sin­gle-as­set CF pact with Ver­tex marks a new phase of deal­mak­ing

Just a few days af­ter Mod­er­na wrapped up a $200 mil­lion-up­front re­search deal with Mer­ck, the Boston biotech is back with an­oth­er pact – this time ty­ing up with crosstown biotech Ver­tex $VRTX on a cys­tic fi­bro­sis de­vel­op­ment agree­ment.

Ver­tex is start­ing out with what amounts to a rel­a­tive­ly small up­front for Mod­er­na, which has struck the moth­er lode of deals with its promise – as yet un­proven in any hu­man tri­als – that your cells can be made in­to drug pro­duc­tion units. Mod­er­na gets $40 mil­lion up­front with half of that com­ing as a con­vert­ible note in­vest­ment. And there’s an­oth­er $275 mil­lion up for grabs in the form of mile­stone pay­ments.

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