Anirvan Ghosh, Unity Biotechnology CEO (Biogen via Facebook)

A sin­gle in­jec­tion of Uni­ty's an­ti-ag­ing hy­poth­e­sis bears fruit in PhII, as piv­otal plans shape up

We all know the scene. Jamie Lee Cur­tis’ char­ac­ter in “Freaky Fri­day” pens a book ti­tled “Through the Look­ing Glass: Senes­cence in Ret­ro­grade,” and she goes on a talk show to pro­mote the work, but it’s not her do­ing the talk­ing — her daugh­ter, played by Lind­say Lo­han, has swapped bod­ies with her and the two must fig­ure out how to re­verse the odd turn of events.

Senes­cent cells have been at the heart of Uni­ty Biotech­nol­o­gy for years, as the biotech has gone through the drug R&D hur­dles try­ing to prove out its an­ti-ag­ing hy­poth­e­sis. On Tues­day, Uni­ty has like­ly found a light at the end of the tun­nel: a piv­otal study of its on­ly clin­i­cal-stage drug is now on tap for Sep­tem­ber 2023 af­ter a Phase II tri­al in di­a­bet­ic mac­u­lar ede­ma proved to be durable out to 24 weeks.

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