Aquinox dis­cards lead drug, chops half of its staff in wake of PhI­II dis­as­ter

When Aquinox con­ced­ed ut­ter fail­ure on its Phase III tri­al two weeks ago, ex­ecs were clear that there was noth­ing left to sal­vage. They are now con­clud­ing that more than half of the staff will have to go with the drug pro­gram.

The re­struc­tur­ing claims 30 em­ploy­ees, ac­count­ing for around 53% of Aquinox’s work­force. The Van­cou­ver-based biotech will al­so close its of­fice in San Bruno, CA while it search­es for a drug can­di­date — most like­ly a SHIP1 ac­ti­va­tor — to re­place rosip­tor.

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