Bone mar­row trans­plant sparks long-term re­mis­sion in sec­ond HIV pa­tient, re­new­ing hope for a cure

The cau­tious­ly op­ti­mistic call it sus­tained re­mis­sion, oth­ers are hope­ful it is a cure — but the doc­tors are im­pressed. An un­named pa­tient in Lon­don, once af­flict­ed with can­cer and the virus that caus­es AIDS, is free of both, cour­tesy an im­mune sys­tem over­haul trig­gered by a bone mar­row trans­plant from an HIV-re­sis­tant donor.

The case comes a dozen years or so af­ter the “Berlin pa­tient” — now iden­ti­fied as Tim­o­thy Ray Brown — who achieved sus­tained re­mis­sion fol­low­ing the same pro­ce­dure for his leukemia. Al­though Brown un­der­went two trans­plants, was giv­en to­tal body ir­ra­di­a­tion no longer in use to­day, and was placed in an in­duced co­ma, he even­tu­al­ly re­cov­ered and was deemed HIV-free. Sci­en­tists took note, and tried re­peat­ed­ly to du­pli­cate the feat, but in vain.

Endpoints News

Unlock this article instantly by becoming a free subscriber.

You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.