British re­searchers be­hind RE­COV­ERY re­turn for mon­key­pox drug study, launch­ing ahead of NIH tri­al

The UK-based Ox­ford Uni­ver­si­ty re­searchers be­hind the suc­cess­ful Covid-19 treat­ment tri­al RE­COV­ERY are back again, this time cob­bling to­geth­er a ran­dom­ized con­trolled tri­al to see if Siga Tech­nolo­gies’ small­pox treat­ment Tpoxx (tecovir­i­mat) is safe and ef­fec­tive for mon­key­pox.

The first par­tic­i­pant en­rolled on Fri­day in the PLAT­INUM (Place­bo-con­trolled ran­dom­ized tri­al of tecovir­i­mat in non­hos­pi­talised mon­key­pox pa­tients) tri­al, build­ing off an­i­mal mod­el suc­cess­es that led to FDA and UK ap­provals, and fol­lows the NIH’s Na­tion­al In­sti­tute of Al­ler­gy and In­fec­tious Dis­eases an­nounce­ment that it’s launch­ing a sim­i­lar tri­al in the US next week.

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