Gly­coMimet­ics shares crash af­ter Pfiz­er team dis­miss­es their lead drug as a PhI­II fail­ure

Close to 8 years ago, the BD team at Pfiz­er signed a $340 mil­lion deal to li­cense in a mid-stage drug from Gly­coMimet­ics for a par­tic­u­lar­ly painful com­pli­ca­tion of sick­le cell dis­ease. There was no ex­act word on the cash in­volved, but the phar­ma gi­ant agreed to fund the en­tire Phase III ef­fort they would need for an ap­proval.

It didn’t work. 

Af­ter the mar­ket closed on Fri­day, the biotech re­port­ed that Pfiz­er ex­ecs had passed on word that the tri­al failed the pri­ma­ry end­point — time to dis­charge readi­ness — as well as key sec­on­daries. We didn’t get the hard num­bers, just the top-line news.

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