J&J looks to toss its SGLT2 hat in the ring for two types of heart fail­ure

In the last year, two SGLT2 in­hibitors — ini­tial­ly de­vel­oped to treat di­a­betes — have snagged ap­provals in the heart fail­ure space. Now John­son & John­son is jump­ing on the band­wag­on, read­ing out pos­i­tive Phase III re­sults for its own SGLT2 drug In­vokana.

Pa­tients who took In­vokana in the CHIEF-HF study saw “sig­nif­i­cant­ly greater im­prove­ments” in their heart fail­ure symp­toms com­pared to place­bo, re­gard­less of their di­a­betes sta­tus, J&J an­nounced at this year’s Amer­i­can Heart As­so­ci­a­tion con­fer­ence.

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