Mauled by a ma­jor set­back, In­cyte is point­ing to a bet­ter fu­ture — but con­cedes it al­so had to scrap an­oth­er failed study

At least In­cyte $IN­CY has Jakafi.

With the biotech’s IDO1 pipeline ef­fort founder­ing on bad da­ta, In­cyte to­day led off the an­nu­al up­date on its R&D ef­fort with some good news. Jakafi, its pri­ma­ry cash con­trib­u­tor, met the pri­ma­ry end­point in a piv­otal study for steroid-re­frac­to­ry acute graft-ver­sus-host dis­ease, set­ting up a near-term sup­ple­men­tal drug ap­pli­ca­tion.

But while ex­ecs al­so spot­light­ed progress among its top-tier de­vel­op­ment ef­forts, In­cyte al­so not­ed that it’s scrap­ping a clin­i­cal tri­al for IN­CB50465, a PI3Kδ drug, af­ter it failed to mea­sure up in pa­tients with dif­fuse large B cell lym­phoma. Three oth­er tri­als for this drug are con­tin­u­ing, with the first cut on re­sults ex­pect­ed in 2019.

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