NewAms­ter­dam Phar­ma res­ur­rects Am­gen's old CETP drug with plans to jump in­to PhI­II this year

Eli Lil­ly thought it found the “holy grail” a decade ago with a CETP in­hibitor that low­ered bad cho­les­terol and raised good cho­les­terol, with oth­ers like Mer­ck, Am­gen, Roche and Pfiz­er jump­ing in the race as well. But when study af­ter study showed the new class of drugs didn’t curb car­dio­vas­cu­lar dis­ease, Big Phar­ma large­ly aban­doned their ef­forts.

NewAms­ter­dam Phar­ma CEO Michael David­son saw an op­por­tu­ni­ty last year to res­ur­rect Am­gen’s old drug — one of the few that didn’t make it to piv­otal stud­ies. And on Wednes­day, he un­veiled the first pos­i­tive Phase II re­sults.

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