
Relmada reports a PhIII fail, blaming 'paradoxical' placebo effect — shares wiped
A Florida biotech attempting to develop a rapid-acting antidepressant ran face-first into a brick wall Thursday.
Relmada Therapeutics reported a Phase III fail for its lead compound, REL-1017, in major depressive disorder, noting the program did not separate from placebo after 28 days in a depression rating scale measuring severe episodes. Though the data were numerically similar, Relmada did not report a p-value to illustrate by how much REL-1017 whiffed.
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