As­traZeneca’s asth­ma drug Fasen­ra looks promis­ing for a set of rare chron­ic im­mune dis­eases

Just 16 months af­ter the FDA ap­proved As­traZeneca’s Fasen­ra for a se­vere form of asth­ma, in­ves­ti­ga­tors at the NIH have found that the drug ap­pears to hold great promise for treat­ing rare chron­ic im­mune dis­or­ders called hy­per­e­osinophilic syn­dromes, or HES.

The team led by Amy Klion, chief of the Hu­man Eosinophil Sec­tion in the NI­AID Lab­o­ra­to­ry of Par­a­sitic Dis­ease, fol­lowed a fa­mil­iar path with this drug, which has al­ready proved its abil­i­ty to flag eosinophils for de­struc­tion, war­rant­i­ng the ap­proval in the fall of 2017 for se­vere asth­ma as­so­ci­at­ed with eosinophils in the lungs.

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