Ax­ing staff and shelv­ing can­cer pro­grams, Se­lec­ta hopes laser fo­cus on gout will prove a way out

As Wern­er Cautreels com­pletes his re­tire­ment form Se­lec­ta Bio­sciences, new CEO Carsten Brunn is left on his own to start the year off with an un­en­vi­able charge: Ex­e­cute a re­vamp that will claim 36% of the com­pa­ny’s work­force.

The lay­offs will main­ly hit the biotech’s on­col­o­gy team, which slammed the brakes on a Phase I study of SEL-403 in the wake of a pa­tient death and lat­er a clin­i­cal hold. That drug, along­side the whole can­cer pipeline, will now be “de­pri­or­i­tized” in fa­vor of its lead drug, SEL-212 for chron­ic re­frac­to­ry gout.

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