No­var­tis qui­et­ly buries an­oth­er failed eczema drug, with a $485M hit em­bed­ded in the foot­notes

Back in late 2016, when Vas Narasimhan was the chief med­ical of­fi­cer at gi­ant No­var­tis, he arranged a buy­out of Ziar­co pri­mar­i­ly so he could get his hands on ZPL389, an oral H4 re­cep­tor an­tag­o­nist that had at­tract­ed him with some de­cent mid-stage da­ta on atopic der­mati­tis. And he gave it a full-throat­ed shoutout in the re­lease, talk­ing up about how ex­cit­ed he was to make a move on the eczema front.

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